发明名称 DIAGNOSIS AND TREATMENT OF CANCER USING ANTI-ITM2A ANTIBODY
摘要 Disclosed is a monoclonal antibody binding to an ITM2A protein. This antibody is useful in the diagnosis, prevention, and treatment of cancer such as Ewing's sarcoma, T cell leukemia, T cell lymphoma, acute myeloid leukemia, B cell tumor, and multiple myeloma. The present invention also provides a pharmaceutical composition, a cell growth inhibitor, and an anticancer agent containing the antibody as an active ingredient, and a method for treating cancer, a method for predicting the efficacy of cancer treatment, and a method for determining the presence of cancer in a test subject using the antibody.
申请公布号 US2014193420(A1) 申请公布日期 2014.07.10
申请号 US201214112590 申请日期 2012.04.18
申请人 Aburatani Hiroyuki;Ishikawa Shumpei;Kawai Shigeto 发明人 Aburatani Hiroyuki;Ishikawa Shumpei;Kawai Shigeto
分类号 C07K16/30;G01N33/574 主分类号 C07K16/30
代理机构 代理人
主权项 1. A monoclonal antibody binding to a fragment of an ITM2A protein having the amino acid sequence represented by SEQ ID NO: 1.
地址 Tokyo JP