| 摘要 |
FIELD: chemistry.SUBSTANCE: described is a novel method for selective production of 5-alkyl-1,3,5-triazinan-2(thi)ones of general formula, where X=O, S; R=t-Bu, cyclohexyl; R'=H, allyl, where a primary aliphatic amine RNH, where R has values given above, reacts with bis(N,N-dimethylamino)methane and (thio)urea in the presence of a copper chloride crystalline hydrate CuCl·2HO catalyst in molar ratio (thio)urea:bis(N,N-dimethylamino)methane:RNH:CuCl·2HO=10:20:10:(0.3-0.7) at temperature of 80°C and atmospheric pressure in a mixture of solvents CHCl-ethyl alcohol (1:1, by volume) for 6-10 hours.EFFECT: obtained compounds have potential for use as effective pesticides and can serve as synthons for producing alkaloid Agelastatina A; output of 5-alkyl-1,3,5-triazinan-2(thi)ones is 22-50%.1 tbl, 1 ex |
