Biomarkers for Ankylosing Spondylitis

摘要

There is described herein methods and peptides for detecting autoantibodies to NOG and/or SOST in a patient sample in order to diagnose of prognosticate Ankylosing Spondylitis in the patient.

主权项

1. A method for diagnosing a subject with Ankylosing Spondylitis comprising:
a. providing a sample from the subject; b. detecting a level of autoantibodies to at least one of NOG and SOST in the sample; c. comparing the level of autoantibodies detected in b. to a level of autoantibodies in a control sample;wherein a relatively higher level of autoantibodies in the subject sample compared to the control sample is indicative of Ankylosing Spondylitis in the subject.