Smartphone Biosensor

摘要

A mobile computing device that includes an image sensor may be used to detect the result of a biomolecular assay. The biomolecular assay may be performed in an optical assay medium that provides an optical output in response to light from a light source, with the optical output indicating result. A wavelength-dispersive element may be used to disperse the optical output into spatially-separated wavelength components. The mobile computing device may be positioned relative to the wavelength-dispersive element such that different wavelength components are received at different locations on the image sensor. With the mobile computing device positioned in this way, the image sensor may be used to obtain one or more images that include the separated wavelength components of the optical output. A wavelength spectrum of the optical output may be determined from the one or more images, and the result may be determined from the wavelength spectrum.

主权项

1. A system, comprising:
a light source; an optical assay medium configured to perform a biomolecular assay and provide an optical output in response to light from the light source, wherein the optical output is indicative of a result of the biomolecular assay; a wavelength-dispersive element, wherein the wavelength-dispersive element is configured to disperse the optical output into spatially-separated wavelength components; a mobile computing device, wherein the mobile computing device includes an image sensor; and a mount configured to removably mount the mobile computing device in a predetermined position relative to the wavelength-dispersive element such that the image sensor can obtain an image of at least a portion of the dispersed optical output, the portion comprising a predetermined range of wavelengths in which different wavelength components are received at different locations on the image sensor.