发明名称 THIOXOTHIAZOLIDINE DERIVATIVE HAVING RAS FUNCTION INHIBITORY EFFECT
摘要 The present invention provides an anticancer drug having a Ras function inhibitory action.;The present invention provides a Ras function inhibitor comprising a compound represented by the formula (I′):;;wherein each symbol is as defined in the present specification, or a salt thereof.
申请公布号 US2014194412(A1) 申请公布日期 2014.07.10
申请号 US201214116152 申请日期 2012.05.09
申请人 Kataoka Tohru;Shima Fumi;Neya Masahiro;Sasahara Daisuke 发明人 Kataoka Tohru;Shima Fumi;Neya Masahiro;Sasahara Daisuke
分类号 C07D417/14;C07D277/36;C07D417/06;C07D417/12 主分类号 C07D417/14
代理机构 代理人
主权项 1. Ras function inhibitor comprising a compound represented by the formula (I′): wherein A is an optionally substituted cyclic group or an optionally substituted chain hydrocarbon group; B is a hydrogen atom, an optionally substituted cyclic group, an optionally substituted amino group, an optionally substituted hydroxy group or an optionally esterified or amidated carboxy group; X1 and X2 are each independently an oxygen atom or a sulfur atom; and Y and Z are each independently a bond or a spacer having 1 to 6 atoms, or a salt thereof.
地址 Kobe-shi JP