| 发明名称 |
ABCA1 DOWNREGULATION IN PROSTATE CANCER |
| 摘要 |
A method of providing a prognosis or diagnosis of prostate cancer in a subject is described. The method includes obtaining a urine or prostate sample from the subject; determining the level of expression of ABCA1 in the sample; and comparing the level of expression of ABCA1 in the sample to the level of a control sample, wherein a decreased level of ABCA1 expression compared to the control indicates the subject has prostate cancer or a more severe form of prostate cancer. Methods of treating subjects identified as having prostate cancer, and kits for carrying out the method of prognosis or diagnosis are also described. |
| 申请公布号 |
US2014193814(A1) |
申请公布日期 |
2014.07.10 |
| 申请号 |
US201414148241 |
申请日期 |
2014.01.06 |
| 申请人 |
The Cleveland Clinic Foundation |
发明人 |
Ting Angela H.;Lee Byron H. |
| 分类号 |
C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of providing a prostate cancer prognosis in a subject having prostate cancer, comprising:
(a) obtaining a urine or prostate sample from the subject; (b) determining the level of expression of ABCA1 in the sample; and (c) comparing the level of expression of ABCA1 in the sample to the level of a control sample, wherein a decreased level of ABCA1 expression compared to the control indicates the subject has a more severe form of prostate cancer. |
| 地址 |
Cleveland OH US |
