| 发明名称 |
MODULATORS OF TNF-αSIGNALING |
| 摘要 |
<p>PROBLEM TO BE SOLVED: To provide modulators of cytokine tumor necrosis factorα(TNF-α) signaling.SOLUTION: The present invention provides compounds of the general formula II, or physiological salts thereof. The present invention also provides pharmaceutical compositions for treating a TNF-αmediated condition which comprise the compounds or salts thereof.</p> |
| 申请公布号 |
JP2014129406(A) |
申请公布日期 |
2014.07.10 |
| 申请号 |
JP20140043411 |
申请日期 |
2014.03.06 |
| 申请人 |
GENZYME CORP |
发明人 |
SNEDDON SCOTT F;KANE JOHN L;HIRTH BRADFORD H;VINICK FRED;QIAO SHUANG;NAHILL SHARON R;JOHN M WILLIAMS;HANS-PETER BIEMANN;JANJIGIAN ANDREW |
| 分类号 |
C07D295/14;C07D401/14;A61K31/277;A61K31/405;A61K31/417;A61K31/4178;A61K31/4439;A61K31/444;A61K31/498;A61K31/506;A61K31/53;A61K31/5375;A61K31/5377;A61P1/04;A61P1/16;A61P3/10;A61P5/00;A61P5/14;A61P7/00;A61P7/02;A61P9/00;A61P9/10;A61P9/14;A61P17/00;A61P19/02;A61P21/04;A61P25/00;A61P25/14;A61P25/28;A61P25/32;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P33/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07C255/60;C07D233/54;C07D233/64;C07D401/12;C07D403/12;C07D403/14;C07D405/12;C07D409/12 |
主分类号 |
C07D295/14 |
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