| 主权项 |
1. A filtration device including at least one filtration unit, the at least one filtration unit comprising:
a first sidewall; a second sidewall; a first fluid inlet defined between the first sidewall and the second sidewall, the first fluid inlet configured to receive a feed comprising a particle population and a fluid; a first row of pillars; a first plurality of pores defined by spacings between adjacent pillars in the first row of pillars, each of the first plurality of pores having an effective pore size smaller than a first physical pore size, the first physical pore size defined by the spacings between the adjacent pillars in the first row of pillars; a first flow chamber defined between the first row of pillars and the second sidewall and including a first flow chamber inlet and a first retentate outlet, the first flow chamber configured to direct a first retentate including at least a portion of the particle population to the first retentate outlet; a second flow chamber defined between the first row of pillars and the first sidewall and including a first filtrate outlet, the second flow chamber configured to direct a first filtrate including at least a portion of the fluid to the first filtrate outlet; wherein a spacing of pillars in the first row of pillars from the first sidewall that are located proximate the first flow chamber inlet being smaller than a spacing of pillars in the first row of pillars from the first sidewall located proximate the first retentate outlet; a second row of pillars; and a second plurality of pores defined by spacings between adjacent pillars in the second row of pillars, each of the second plurality of pores having an effective pore size smaller than a second physical pore size, the second physical pore size defined by the spacings between the adjacent pillars in the second row of pillars. |
