TOPICAL PHARMACEUTICAL COMPOSITIONS OF ANTI-MICROBIAL AGENTS AND ANTI-INFLAMMATORY AGENTS.

摘要

The present invention provides sterile, storage-stable topical pharmaceutical compositions intended for application to the eye, ear or nose comprising Dexamethsone and Ciprofloxacin. The topical pharmaceutical compositions of invention comprises combination of ionic tonicity agent and non-ionic tonicity agent(s). The topical pharmaceutical compositions further comprises boric acid. The invention provides a process for preparing and sterilizing the compositions in order to reduce the amount of related compounds and impurities associated with the topical compositions on storage. The topical pharmceutical compositions of invention found storage-stable, have easy resuspendability.