发明名称 METHODS OF INHIBITING TUMOR GROWTH BY ANTAGONIZING IL-6 RECEPTOR.
摘要 The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain embodiments, the methods of the invention are used to inhibit the growth of an anti-VEGF-resistant tumor in a subject. The IL-8 antagonist may be, e.g., an antibody that spectficaiiy binds SL-6R, The 11-6 antagonist may be administered in combination with a VEGF antagonist, and/or an EGFR antagonist.
申请公布号 MX2014004886(A) 申请公布日期 2014.07.09
申请号 MX20140004886 申请日期 2012.11.09
申请人 REGENERON PHARMACEUTICALS, INC. 发明人 LI ZHANG
分类号 C07K16/28;A61K39/395;A61P35/00;C07K16/32 主分类号 C07K16/28
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