| 发明名称 |
SOLUBLE MEDIATOR |
| 摘要 |
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of CD52, and to diagnostic methods based on the detection of CD52 expression levels in a subject. |
| 申请公布号 |
EP2750690(A1) |
申请公布日期 |
2014.07.09 |
| 申请号 |
EP20120850386 |
申请日期 |
2012.11.15 |
| 申请人 |
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH |
发明人 |
BANDALA SANCHEZ, ESTHER;DROMEY, JAMES;HARRISON, LEONARD CHARLES;ZHANG, YUXIA;RASHIDI, MARYAM |
| 分类号 |
A61K38/10;A61K38/28;A61P5/50;A61P37/06;C12N15/12;C12N15/86;G01N33/15 |
主分类号 |
A61K38/10 |
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