| 发明名称 |
PEPTIDE ABLE TO DISRUPT THE PROTEIN COMPLEX BETWEEN THE HIS273 MUTATED P53 PROTEIN AND THE ONCOSUPPRESSIVE P73 PROTEIN IN TUMOUR CELLS AND THERAPEUTIC USES THEREOF |
| 摘要 |
<p>The present invention concerns a SIMP peptide (Short-interfering mutant p53 peptides) suitable to disrupt the protein complexes within tumour cells resulting from m-p53 and p73 proteins selectively in tumours wherein m-p53 contains His273 mutation.</p> |
| 申请公布号 |
EP2429563(B1) |
申请公布日期 |
2014.07.09 |
| 申请号 |
EP20100736805 |
申请日期 |
2010.05.06 |
| 申请人 |
ISTITUTI FISIOTERAPICI OSPITALIERI |
发明人 |
CITRO, GENNARO;BLANDINO, GIOVANNI;STRANO, SABRINA;DI AGOSTINO, SILVIA |
| 分类号 |
A61K38/08;A61K38/10;A61K38/17;A61P35/00 |
主分类号 |
A61K38/08 |
| 代理机构 |
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