发明名称 Cysteine protease inhibitors
摘要 <p>There is provided a process for the preparation of a compound of formula III, comprising the step of oxidising the compound of formula 2b wherein n is 2; R 2a and R 2b are independently H or F; R 3 is 1-methylcyclopentylmethyl or 1-fluorocyclopentylmethyl; R 3' is CH 3 or F; R 4 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl or C 3 -C 6 cycloalkyl, wherein C 3 -C 6 cycloalkyl is optionally substituted with methyl, CF 3 or one or two fluoro. Compounds and processes used in the preparation of a compound of formula III are also provided.</p>
申请公布号 EP2752404(A1) 申请公布日期 2014.07.09
申请号 EP20140162956 申请日期 2011.06.16
申请人 MEDIVIR UK LTD 发明人 AYESA, SUSANA;GRABOWSKA, URSZULA;HEWITT, ELLEN;JÖNSSON, DANIEL;WIKTELIUS, DANIEL;KLASSON, BJORN;KAHNBERG, PIA;LUNDGREN, STINA;TEJBRANT, JAN
分类号 C07C237/14;A61K31/16;A61P11/00;A61P37/00;C07D233/58 主分类号 C07C237/14
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