MELT-EXTRUDED RELEASE CONTROLLED PHARMACEUTICAL COMPOSITION AND ORAL DOSAGE FORM COMPRISING THE SAME

摘要

The present invention relates to a release-controlled pharmaceutical composition and an oral dosage form including the same, wherein the release-controlled pharmaceutical composition comprises the following: a melt-extruded pellet including a water-insoluble ammonium methacrylate copolymer, polyvinyl acetate, and active components; and a polymer coating layer including the water-insoluble ammonium methacrylate copolymer formed on the surface of the pellet.