Method of treating cancer using combination of a bifunctional alkylating agent and DNA repair inhibitors

摘要

A pharmaceutical composition for treating cancer, in particular drug resistant cancer, comprising an effective amount of bifunctional alkylating agent, an effective amount of a DNA repair inhibitor, and a pharmaceutically acceptable carrier.

主权项

1. A pharmaceutical composition for treating cancer comprising an effective amount of a derivative of 3a-aza-cyclopentaindene selected from the group consisting of BO-1012, an effective amount of a DNA repair inhibitor, and a pharmaceutically acceptable carrier.