发明名称 |
Alpha B-crystallin as a therapy for ischemia or inflammation |
摘要 |
The invention provides methods for treating inflammatory diseases by administering to the subject an effective amount of an agent that provides alpha B-crystallin activity, where the dose is effective to suppress or prevent initiation, progression, or relapses of disease, including the progression of established disease. In some embodiments, the methods of the invention comprise administering to a subject having a pre-existing inflammatory disease condition, an effective amount of alpha B-crystallin protein, to suppress or prevent relapses of the disease. |
申请公布号 |
US8771689(B2) |
申请公布日期 |
2014.07.08 |
申请号 |
US201113135079 |
申请日期 |
2011.06.23 |
申请人 |
The Board of Trustees of the Leland Stanford Junior University;Department of Veterans Affairs |
发明人 |
Steinman Lawrence;Ousman Shalina Sheryl;Robinson William H. |
分类号 |
A61K39/395;A61K38/00 |
主分类号 |
A61K39/395 |
代理机构 |
Bozicevic, Field & Francis LLP |
代理人 |
Bozicevic, Field & Francis LLP ;Sherwood Pamela J. |
主权项 |
1. A method for inhibiting neuromyelitis optica in a patient, the method comprising:
administering to said patient a therapeutically effective dose of alpha B-crystallin protein. |
地址 |
Palo Alto CA US |