发明名称 |
Tetrahydropyrrolothiazine compounds |
摘要 |
The present invention provides compounds of Formula I:;
wherein A is selected from the group consisting of;
;R1 is H or F;R2 is H, —CH2OH, C1-C3 alkyl,;R3 is H, F, or CN;R4 is H, F; or CN; andR5 is H, —CH3, or —OCH3;
or a pharmaceutically acceptable salt thereof. |
申请公布号 |
US8772282(B2) |
申请公布日期 |
2014.07.08 |
申请号 |
US201314096443 |
申请日期 |
2013.12.04 |
申请人 |
Eli Lilly and Company |
发明人 |
Beck James Peter;Green Steven James;Lopez Jose Eduardo;Mathes Brian Michael;Mergott Dustin James;Porter Warren Jaye;Rankovic Zoran;Shi Yuan;Watson Brian Morgan;Winneroski, Jr. Leonard Larry |
分类号 |
A61K31/542 |
主分类号 |
A61K31/542 |
代理机构 |
|
代理人 |
Lentz Nelsen L. |
主权项 |
1. A pharmaceutical composition comprising a compound of the formula: wherein A is selected from the group consisting of; R1 is H or F; R2 is H, —CH2OH, C1-C3 alkyl, R3 is H, F, or CN; R4 is H, F; or CN; and R5 is H, —CH3, or —OCH3; or a pharmaceutically acceptable salt thereof, in combination with one or more pharmaceutically acceptable carriers, diluents, or excipients. |
地址 |
Indianapolis IN US |