发明名称 |
EVOLVING NEW MOLECULAR FUNCTION |
摘要 |
Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of'organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety-of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis. |
申请公布号 |
CA2495881(C) |
申请公布日期 |
2014.07.08 |
申请号 |
CA20032495881 |
申请日期 |
2003.08.19 |
申请人 |
THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LIU, DAVID R.;GARTNER, ZEV J.;DOYON, JEFFREY B.;CALDERONE, CHRISTOPHER T.;KANAN, MATTHEW W.;LI, XIAOYU;SNYDER, THOMAS M.;ROSENBAUM, DANIEL M. |
分类号 |
C12N15/09;C12P19/34;C07H21/00;C12N15/10;C12P41/00;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|