发明名称 |
Transformant for enhancing bioethanol production, and method for producing ethanol by using said strain |
摘要 |
The present invention relates to a transformant for inhibiting glycerol production through deletion of glycerol producing genes of Saccharomyces cerevisiae modified so as to use glycerol as a fermentation source, or enhancing bioethanol production through overexpression of TATA-binding proteins, SPT3 and SPT15, and a method for producing ethanol by using the transformant. |
申请公布号 |
US8772000(B2) |
申请公布日期 |
2014.07.08 |
申请号 |
US201113641946 |
申请日期 |
2011.04.15 |
申请人 |
Korea University Research and Business Foundation |
发明人 |
Han Sung Ok;Yu Kyung Ok;Kim Seung Wook |
分类号 |
C12P7/06;C12N1/19;C12R1/865;C12N9/04;C12N9/12;C12N9/88;C07K14/39 |
主分类号 |
C12P7/06 |
代理机构 |
Hultquist, PLLC |
代理人 |
Hultquist, PLLC ;Hultquist Steven J.;Grant Mary B. |
主权项 |
1. A genetically engineered yeast cell, wherein said cell comprises: a disruption of a gene encoding glycerol-3-phosphate dehydrogenase 2 and a disruption of a FPS1 (glycerol facilitator channel) gene encoding yeast glycerol channel FPS1, wherein said cell further comprises a gene encoding glycerol dehydrogenase, a gene encoding dihydroxyacetone kinase, and a gene encoding glycerol uptake protein, wherein said cell comprises a gene encoding Saccharomyces cerevisiae pyruvate decarboxylase and a gene encoding alcohol dehydrogenase, wherein said cell is Saccharomyces cerevisiae YPH499fps1Δgpd2Δ (pGcyaDakAdhPdc, pGupCas), wherein the accession number of Saccharomyces cerevisiae YPH499fps1Δgpd2Δ (pGcyaDakAdhPdc, pGupCas) is KCCM11152P. |
地址 |
Seoul KR |