发明名称 Micronized tanaproget, compositions, and methods of preparing the same
摘要 The present invention provides compositions, desirably pharmaceutical compositions, containing micronized tanaproget. The compositions can also contain microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, magnesium stearate, micronized edetate calcium disodium hydrous, and micronized sodium thiosulfate pentahydrate. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefor. Additional uses include stimulation of food intake.
申请公布号 US8772271(B2) 申请公布日期 2014.07.08
申请号 US201313890523 申请日期 2013.05.09
申请人 Wyeth LLC 发明人 Nagi Arwinder S.;Chatlapalli Ramarao;Hasan Shamim;Ghorab Mohamed;Gaglani Dhaval
分类号 A61K31/335;A61K31/56;C07D295/00;C07D265/12 主分类号 A61K31/335
代理机构 Howson & Howson LLP 代理人 Howson & Howson LLP
主权项 1. A kit comprising a pharmaceutical composition comprising an intragranulation comprising micronized tanaproget or a pharmaceutically acceptable salt thereof, microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, magnesium stearate, micronized edetate calcium disodium hydrous, and micronized sodium thiosulfate pentahydrate.
地址 Madison NJ US