发明名称 |
Chimeric molecule and nucleic acid encoding same |
摘要 |
The present invention relates, in general, to telomeres, and, in particular, to a method or effecting telomere elongation in mammalian cells. The invention further relates to a protein suitable for use in such a method and to nucleic acid sequences encoding same. |
申请公布号 |
US8771982(B2) |
申请公布日期 |
2014.07.08 |
申请号 |
US200410554295 |
申请日期 |
2004.04.30 |
申请人 |
Duke University |
发明人 |
Counter Christopher M.;Armbruster Blaine N. |
分类号 |
C12P21/06;C12N9/00;C12N9/22;C12N1/20;C12N15/00;C07H21/04 |
主分类号 |
C12P21/06 |
代理机构 |
Nixon & Vanderhye P.C. |
代理人 |
Nixon & Vanderhye P.C. |
主权项 |
1. An isolated nucleic acid sequence encoding a chimeric molecule comprising a polypeptide having telomerase catalytic activity fused to a telomere binding polypeptide wherein said nucleic acid sequence comprises the nucleotide sequence set forth in SEQ ID NO:1. |
地址 |
Durham NC US |