发明名称 |
Inducible release vehicles |
摘要 |
This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and/or nutraceutical applications. |
申请公布号 |
US8771650(B2) |
申请公布日期 |
2014.07.08 |
申请号 |
US201113268108 |
申请日期 |
2011.10.07 |
申请人 |
Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO |
发明人 |
Thijssen Henricus Matheus Wilhelmus Maria;Montijn Roy Christiaan;Timmermans Johannes Wilhelmus;Slaghek Theodoor Maximiliaan;van Veen Jacobus Johannes Frederik;Boumans Johannes Wilhelmus Leonardus |
分类号 |
A01P3/00;A61K38/00;A61P17/10;A61K9/16;A01N63/00;A61K9/68;A61K47/36;A61Q15/00;A61Q19/00;A01N25/00;A23L1/22;A01N25/04;A61K47/38;A01P1/00;A01N25/10;A61K47/42;A61L9/01 |
主分类号 |
A01P3/00 |
代理机构 |
Preti Flaherty Beliveau & Pachios LLP |
代理人 |
Preti Flaherty Beliveau & Pachios LLP |
主权项 |
1. A method to induce release of an active component from a vehicle, the method comprising
providing a vehicle comprising a charged cross-linked carbohydrate consisting of only C-, O- and H-atoms and an active component; and contacting the vehicle with an enzyme external to the vehicle with specificity for the degradation of the carbohydrate, whereby the carbohydrate is degraded and the active component is released, wherein release of the active component does not occur in an aqueous medium until release thereof is triggered by the enzyme external to the vehicle being contacted with the vehicle. |
地址 |
Delft NL |