Medical devices with selective titanium oxide coatings

摘要

Medical devices, such as endoprostheses, and methods of making the devices are described. In some embodiments, a medical device includes a body of interconnected bands and connectors forming an elongated tubular structure having an inner luminal wall surface and an outer abluminal wall surface and defining a central lumen or passageway. The inner luminal wall surface and side wall surface of the bands and connectors forming transverse passageways through the elongated tubular structure can bear a coating of hydrophilic material and the outer abluminal wall surface of the tubular structure can bear a coating of hydrophobic material.

主权项

1. A medical device comprising:
an elongated tubular structure having an inner luminal wall surface, an outer abluminal wall surface, and side wall surfaces extending therebetween, a first coating on at least one or more regions of the luminal wall surface and/or the side wall surfaces comprising a material comprising titanium (+y) oxide (−x), a second coating on at least one or more regions of the abluminal wall surface comprising the material comprising the titanium (+y) oxide (−x),
the material in one of the first coating and the second coating being hydrophobic and the one of the first coating and the second coating being hydrophobic, and the material in another of the first coating and the second coating being hydrophilic and the other one of the first coating and the second coating being hydrophilic, and a layer of organic compound over the first and second coatings.