发明名称 SALTS OF HIV INHIBITOR COMPOUNDS
摘要 PROBLEM TO BE SOLVED: To provide salts of HIV inhibitor compounds.SOLUTION: The invention relates to salts of antiviral compounds, a composition containing such salts, a treatment method containing administration of such salts, a process and an intermediate useful for manufacturing such salts. The invention provides stable salts of ethyl N-[(S)-({[(2R,5R)-5-(6-amino-9H-purine-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]oxy}methyl)phenoxyphosphinoyl]-L-alaninate which is physically more stable, easier to isolate and formulate than a free base type of the compound.
申请公布号 JP2014122235(A) 申请公布日期 2014.07.03
申请号 JP20140054797 申请日期 2014.03.18
申请人 GILEAD SCIENCES INC 发明人 GRAETZ BENJAMIN R;RICHARD P POLNIASZEK
分类号 C07F9/6558;A61K31/664;A61K45/00;A61P31/18;C07C55/08;C07C55/10;C07C59/265 主分类号 C07F9/6558
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