发明名称 |
HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND |
摘要 |
<p>Provided is a novel a-halogen substituted thiophene compound which has strong LPA receptor antagonist activity and is useful as a pharmaceutical product, or a pharmacologically acceptable salt thereof. A compound represented by general formula (I) or a salt thereof. (In the formula, A represents a phenyl ring, a thiophene ring or an isothiazole ring; R1 moieties may be the same or different and each represents a halogen atom or a C1-C3 alkyl group; R2 represents a hydrogen atom or a C1-C6 alkyl group; p represents an integer of 0-5; V represents a CR3 group (wherein R3 represents a hydrogen atom, an amino group, a nitro group or a C1-C3 alkoxy group) or a nitrogen atom; and X represents a halogen atom.)</p> |
申请公布号 |
CA2896701(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
CA20132896701 |
申请日期 |
2013.12.27 |
申请人 |
UBE INDUSTRIES, LTD. |
发明人 |
IWASE, NORIAKI;NISHIDA, HIROSHI;OKUDO, MAKOTO;ITO, MASAAKI;KONO, SHIGEYUKI;MATOYAMA, MASAAKI;USHIYAMA, SHIGERU;OKANARI, EIJI;MATSUNAGA, HIROFUMI;NISHIKAWA, KENJI;KIMURA, TOMIO |
分类号 |
C07D333/36;A61K31/381;A61K31/427;A61K31/443;A61P13/00;A61P25/00;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07D409/04;C07D409/14;C07D417/12 |
主分类号 |
C07D333/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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