| 摘要 |
A method of preparing a compound represented by Structural Formula (I):;;or a pharmaceutically acceptable salt thereof, wherein the variables of Structural Formula (I) are as described in the specification and claims, comprises the step of:
a) cyclizing a compound represented by Structural Formula A:;;under suitable reductive cyclisation conditions to form a compound represented by Structural Formula B:;;wherein R10 is LG1 or —X1R1, and -LG1 is a suitable leaving group; and
b) optionally, when R10 of Structural Formula (B) is LG1, further comprising the step of replacing the -LG1 of Structural Formula (B) with —X1R1 to form the compound represented by Structural Formula (I). |
