| 主权项 |
1. A cartridge assembly for use with an injection system, comprising:
an ampule containing a pharmaceutical product, wherein the ampule is sealed at a distal end with a pierceable diaphragm; and a hub comprising (i) a proximal portion defining a cavity that is configured to engage the distal end of the ampule, and (ii) a piercing member positioned within the cavity, wherein the piercing member comprises a fluid pathway between a proximal end portion comprising an opening and a distal end in fluid communication with a distal opening of the hub, wherein the proximal end portion engages the pierceable diaphragm, wherein the hub is configured to engage the ampule in an inactivated position in which the piercing member is not in fluid communication with the pharmaceutical product in the ampule and an activated position in which the proximal end portion of the piercing member is in fluid communication with the pharmaceutical product in the ampule, and wherein the piercing member applies force to the pierceable diaphragm in the inactivated position without penetrating the pierceable diaphragm. |
