发明名称 |
STERILE OPHTHALMIC PHARMACEUTICAL SUSPENSIONS |
摘要 |
<p>An aqueous suspension of a carbonic anhydrase inhibitor such as brinzolamide as well as methods of preparation thereof, are disclosed. The suspension comprises an organic polar solvent such as dimethyl sulfoxide and/or a non-aromatic non-ionic polyethoxylated surfactant such as polyethoxylated castor oil and/or or polysorbate 80. Methods include precipitating brinzolamide from the heated composition. Methods also include sonication of the suspension to reduce brinzolamide particle size.</p> |
申请公布号 |
WO2014105635(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
WO2013US76556 |
申请日期 |
2013.12.19 |
申请人 |
SENTISS PHARMA PVT.LTD.;SHAH, MANDAR V |
发明人 |
SHAH, MANDAR V;BAHRI, DEEPAK |
分类号 |
A61K31/54;A61P27/02 |
主分类号 |
A61K31/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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