| 摘要 |
<p>The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.</p> |
| 申请人 |
NOVARTIS AG |
发明人 |
COOKE, NIGEL GRAHAM;FERNANDES GOMES DOS SANTOS, PAULO ANTONIO;FURET, PASCAL;HEBACH, CHRISTINA;HOGENAUER, KLEMENS;HOLLINGWORTH, GREGORY;KALIS, CHRISTOPH;LEWIS, IAN;SMITH, ALEXANDER BAXTER;SOLDERMANN, NICOLAS;STAUFFER, FREDERIC;STRANG, ROSS;STOWASSER, FRANK;TUFILLI, NICOLA;VON MATT, ANETTE;WOLF, ROMAIN;ZECRI, FREDERIC |
