发明名称 |
METHOD AND SYSTEM FOR DETERMINING WHETHER ARTERIAL TISSUE COMPRISES ATHEROSCLEROTIC PLAQUE |
摘要 |
Provided herein are methods and systems to determine at least one mechanical property of a tissue sample and, based upon the determined at least one mechanical property, whether the tissue sample comprises atherosclerotic plaque. The method comprises generating a shear wave in an arterial tissue sample by applying an acoustic impulse thereto; measuring propagation of the shear wave via an optical coherence elastography apparatus; determining at least one mechanical property of the arterial tissue sample based on the propagation of the shear wave; and comparing the at least one mechanical property of the arterial tissue sample to a reference data set to determine whether the arterial tissue sample comprises atherosclerotic plaque. A hybrid optical coherence tomography imaging/acoustic radiation force impulse system is disclosed. |
申请公布号 |
US2014187904(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
US201314141584 |
申请日期 |
2013.12.27 |
申请人 |
RAZANI Marjan;MARIAMPILLAI Adrian Linus Dinesh;YANG Victor X. D.;KOLIOS Michael |
发明人 |
RAZANI Marjan;MARIAMPILLAI Adrian Linus Dinesh;YANG Victor X. D.;KOLIOS Michael |
分类号 |
A61B5/00 |
主分类号 |
A61B5/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method comprising:
generating a shear wave in an arterial tissue sample by applying an acoustic impulse thereto; measuring propagation of the shear wave via an optical coherence elastography apparatus; determining at least one mechanical property of the arterial tissue sample based on the propagation of the shear wave; and comparing the at least one mechanical property of the arterial tissue sample to a reference data set to determine whether the arterial tissue sample comprises atherosclerotic plaque. |
地址 |
Toronto CA |