Certain quinolizidine and octahydropyridopyrazine compounds, pharmaceutical compositions, and methods of their use, inter alia, as opioid receptor antagonists are disclosed.
申请公布号
US2014186951(A1)
申请公布日期
2014.07.03
申请号
US201414202390
申请日期
2014.03.10
申请人
Adolor Corporation
发明人
Dolle Roland E.;Le Bourdonnec Bertrand;Goodman Allan James
分类号
C07D471/04
主分类号
C07D471/04
代理机构
代理人
主权项
1. A compound of formula I: wherein:
R1 is —C(═O)NH2;X is N—C(═O)-aryl;or a pharmaceutically acceptable salt thereof.