发明名称 METHODS OF PRODUCING 7-CARBON CHEMICALS FROM LONG CHAIN FATTY ACIDS VIA OXIDATIVE CLEAVAGE
摘要 <p>This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the fatty acid synthesis pathway and oxidative cleavage of long chain acyl-[acp] intermediates by a monooxgenase (e.g., cytochrome P450) such as that encoded by BioI from microorganisms such as Bacillus subtillis.</p>
申请公布号 WO2014105793(A1) 申请公布日期 2014.07.03
申请号 WO2013US77419 申请日期 2013.12.23
申请人 INVISTA NORTH AMERICA S.A.R.L. 发明人 BOTES, ADRIANA LEONORA;CONRADIE, ALEX VAN ECK;CHEN, CHANGLIN;PEARLMAN, PAUL S.
分类号 C12P7/18;C12P7/42;C12P7/44;C12P13/00 主分类号 C12P7/18
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