| 摘要 |
PROBLEM TO BE SOLVED: To provide an optical method for detecting Alzheimer disease.SOLUTION: The main subject of the present invention relates to a non-invasive optical imaging method for monitoring an initial pathological event (e.g., generation of amyloid plaque, the amount and position thereof) specific to Alzheimer disease (AD). The capability of monitoring such an event provides a basis for AD diagnosis, prognosis prediction and potential therapy evaluation, above all. Further, the main subject of the present invention is to introduce a new method for treating AD and a retinal disease related with AD. A&bgr; plaque detection is extremely limited particularly in terms of high resolution. Therefore, the present invention is based on a study focusing on an eye, as alternative means of a tissue from the brain, which can be directly, repeatedly and non-invasively imaged. |
