| 发明名称 |
OLIGOMER-OPIOID AGONIST CONJUGATES |
| 摘要 |
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer. |
| 申请公布号 |
US2014187790(A1) |
申请公布日期 |
2014.07.03 |
| 申请号 |
US201314032780 |
申请日期 |
2013.09.20 |
| 申请人 |
NEKTAR THERAPEUTICS |
发明人 |
RIGGS-SAUTHIER Jennifer;DENG Bo-Liang;RILEY Timothy A. |
| 分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound comprising a residue of an opioid agonist having the structure covalently attached to a water-soluble, non-peptidic oligomer through a spacer moiety; or a pharmaceutically acceptable salt thereof. |
| 地址 |
San Francisco CA US |
