摘要 |
The present invention is directed toward novel compounds and novel methods of use of said compounds of the formula (I), useful as nucleocapsid assembly inhibitors for the treatment of viruses, especially but not exclusively, including pregenomic RNA encapsidation inhibitors of HBV for the treatment of Hepatitis B virus (HBV) infection and related conditions. (Formula (I)) Including hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, wherein A, R1, R2, R3, R4, R5, R6, R7, and R8 are defined herein. |
申请人 |
DREXEL UNIVERSITY;ENANTIGEN THERAPEUTICS, INC.;BARUCH S. BLUMBERG INSTITUTE |
发明人 |
BAUGH, SIMON DAVID PETER;YE, HONG;XU, XIAODONG;GUO, JU-TAO;XIAO, TONG;DU, YANMING;BLOCK, TIMOTHY |