摘要 |
A process for preparing nanocapsules having a core-shell structure, comprising: (a) preparing an oil-in-water emulsion by emulsification of an oily phase that comprises a core material, in an aqueous phase, under high shear forces, wherein one or both of the oily phase, and the aqueous phase comprises a sol-gel precursor; (b) subjecting the emulsion obtained in (a) to a high pressure homogenization to obtain a nano-emulsion; and (c) applying conditions for hydrolyzing and polycondensing the sol-gel precursor to obtain nanocapsules having a metal oxide shell encapsulating the core material, said nanocapsules have a particle size distribution of: d10 = 10-80 nm, d50 = 30-200 nm, and d90 = 70-500 nm, in diameter. The invention also relate to nanocapsules having the above particle size distribution and to composition comprising the nanocapsules. |
申请人 |
SOL-GEL TECHNOLOGIES LTD. |
发明人 |
TOLEDANO, OFER;SHAPIRO, LEORA;SERTCHOOK, HANAN;ABU-REZIQ, RAED;BAR-SIMANTOV, HAIM |