发明名称 |
Non Human Animal Models for Increased Retinal Vascular Permeability |
摘要 |
The present invention relates to a non human animal model for increased retinal vascular permeability wherein said increased retinal vascular permeability is induced by inhibiting in Müller cells of said animal the expression of a gene encoding for Dp71 or a dystrophin associated protein (DAP). Furthermore, the present invention relates to methods and compositions for the treatment of a disease associated with an increased retinal vascular permeability in a subject in need thereof. |
申请公布号 |
US2014186960(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
US201414174963 |
申请日期 |
2014.02.07 |
申请人 |
Institut National De La Sante et De La Recherche Medicale (INSERM) |
发明人 |
Sene Abdoulaye;Tadayoni Ramin;Sahel Jose;Rendon Alvaro |
分类号 |
A01K67/027;G01N33/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Paris FR |