发明名称 HETERODIMERIZED POLYPEPTIDE
摘要 The present inventors have succeeded in the production of a heterodimerized polypeptide having an Fc region that is composed of two polypeptides (i.e., a first polypeptide and a second polypeptide) comprising different amino acid sequences from each other. Thus, a heterodimerized polypeptide having an Fc region and having an improved function compared with that of a homodimer having an Fc region composed only of the first polypeptide or a homodimer having an Fc region composed only of the second polypeptide, which are the conventional techniques, can be produced successfully.
申请公布号 WO2014104165(A1) 申请公布日期 2014.07.03
申请号 WO2013JP84809 申请日期 2013.12.26
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 IGAWA, TOMOYUKI;MIMOTO, FUTA;KATADA, HITOSHI;SHIRAIWA, HIROTAKE
分类号 C12N15/09;A61K39/395;A61P35/00;A61P37/00;C07K16/46;C12P21/08 主分类号 C12N15/09
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