发明名称 |
HETERODIMERIZED POLYPEPTIDE |
摘要 |
The present inventors have succeeded in the production of a heterodimerized polypeptide having an Fc region that is composed of two polypeptides (i.e., a first polypeptide and a second polypeptide) comprising different amino acid sequences from each other. Thus, a heterodimerized polypeptide having an Fc region and having an improved function compared with that of a homodimer having an Fc region composed only of the first polypeptide or a homodimer having an Fc region composed only of the second polypeptide, which are the conventional techniques, can be produced successfully. |
申请公布号 |
WO2014104165(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
WO2013JP84809 |
申请日期 |
2013.12.26 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
IGAWA, TOMOYUKI;MIMOTO, FUTA;KATADA, HITOSHI;SHIRAIWA, HIROTAKE |
分类号 |
C12N15/09;A61K39/395;A61P35/00;A61P37/00;C07K16/46;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|