VACCINES AND METHODS FOR USING THE SAME

摘要

Improved anti-HIV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus sequences for HIV Subtype A Envelope protein, those having consensus sequences for HIV Subtype B Envelope protein, those having consensus sequences for HIV Subtype C Envelope protein, those having consensus sequences for HIV Subtype D Envelope protein, those having consensus sequences for HIV Subtype B consensus Nef-Rev protein, and those having consensus sequences form HIV Gag protein subtypes A, B, C and D. Improved anti-HPV immunogens and nucleic acid molecules that encode them; improved anti-HCV immunogens and nucleic acid molecules that encode them; improved hTERT immunogens and nucleic acid molecules that encode them; and improved anti-Influenza immunogens and nucleic acid molecules that encode them are disclosed as well methods of inducing an immune response in an individual against HIV, HPV, HCV, hTERT and Influenza are disclosed.

主权项

1. A nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of: SEQ ID NO:34; fragments of SEQ ID NO:34 comprising 30 or more nucleotides; sequences having at least 90% homology to SEQ ID NO:34; fragments of sequences having at least 90% homology to SEQ ID NO:34.