| 摘要 |
<p>A bioreactor (1) comprises one or more cell culture chambers (8) each containing an interchangeable scaffold (10) for the three dimensional culture of cells, one or more cell media chambers (2) for containing cell culture media, the cell media chamber (s) connected to the cell culture chamber (s) via one or more media flow channels (4, 47), and a pump (6) for pumping cell culture media through the media flow channel (s) from the cell media chamber (s) to the cell culture chamber (s). The bioreactor preferably comprises a nano wire- based detection system for the detection of target molecules using a measure of current/voltage changes in the nano wire. The bioreactor can preferably simultaneously measure several different biological indicator molecules, and enable molecular cellular responses to be monitored via simultaneous real-time measurement of multiple biological indicator molecules.</p> |
