发明名称 |
A METHOD FOR PREDICTING CLINICAL BENEFIT IN THE TREATMENT OF NEURODEVELOPMENTAL, NEUROLOGICAL OR NEUROPSYCHIATRIC DISORDERS |
摘要 |
<p>An in vitro method of predicting whether a patient, having a neurodevelopmental, neurological or neuropsychiatric disorder, will derive a clinical benefit if treated with a glycine reuptake inhibitor (GRI), via determination of the protein concentration of one, two, three, four five or six members of the complement factor H family or a mixture or a combination thereof and comparison against a representative value, wherein a higher value of the protein concentration in the patient's sample against the representative value is indicative of a patient whom will derive clinical benefit from treatment with GRI.</p> |
申请公布号 |
EP2748610(A1) |
申请公布日期 |
2014.07.02 |
申请号 |
EP20120748693 |
申请日期 |
2012.08.21 |
申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
ESSIOUX, LAURENT;HORN, CARSTEN;KARL, JOHANN;KASTNER, PETER;MODEL, FABIAN;PALERMO, GIUSEPPE;RABE, CHRISTINA;UMBRICHT, DANIEL;VARGAS, GABRIEL;VOGT, ANNE |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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