发明名称 |
TETRAHYDROCARBOLINE DERIVATIVE |
摘要 |
An object of the present invention is to provide a drug having the inhibitory activity on ENPP2 which is a different target from that of the existing drug, as a medicament useful in a urinary excretion disorder patient for whom the existing drug has the insufficient effect. The present invention provides a compound represented by the general formula (I):
(wherein definition of each group is as defined in the description) having the ENPP2 inhibitory activity, a salt thereof or a solvate thereof or a prodrug thereof, and an agent for preventing or treating urinary excretion disorder and/or improving symptoms thereof, containing them as an active ingredient. |
申请公布号 |
EP2687531(A4) |
申请公布日期 |
2014.07.02 |
申请号 |
EP20120761051 |
申请日期 |
2012.01.05 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
OHATA, AKIRA;NAKATANI, SHINGO;SUGIYAMA, TETSUYA;MORIMOTO, TAKASHI |
分类号 |
C07D471/04;A61K31/437;A61K31/4375;A61K31/444;A61K31/4545;A61K31/496;A61K31/497;A61K45/00;A61K45/06;A61P11/00;A61P13/00;A61P13/08;A61P17/00;A61P19/02;A61P21/00;A61P29/00;A61P35/00;A61P43/00;C07D471/14 |
主分类号 |
C07D471/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|