| 发明名称 |
AGR2 BLOCKING ANTIBODY AND USE THEREOF |
| 摘要 |
Disclosed is an AGR2 blocking monoclonal antibody, and in particular, a humanized monoclonal antibody for blocking AGR2. Also disclosed is a pharmaceutical composition containing the antibody and a method for preparing the same, and a use of the antibody in blocking tumor growth and metastasis. |
| 申请公布号 |
EP2749573(A1) |
申请公布日期 |
2014.07.02 |
| 申请号 |
EP20120807760 |
申请日期 |
2012.07.05 |
| 申请人 |
SANOFI (CHINA) INVESTMENT CO., LTD. SHANGHAI BRANCH;SHANGHAI JIAO TONG UNIVERSITY |
发明人 |
LI, DAWEI;WU, ZHENGHUA;GUO, HAO;ZHU, QI;MASHAUSI, DHAHIRI S. |
| 分类号 |
C07K16/40;A61K39/395;A61P35/00;C07K16/22;C12N5/10;C12N15/13;C12N15/63;C12P21/08 |
主分类号 |
C07K16/40 |
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