Hydrophilic crosslinked polymer

摘要

The present invention relates to a hydrophilic crosslinked polymer, preferably in the form of porous particles, and to the preparation and use thereof. The polymer according to the invention is produced by polymerization from chain-forming hydrophilic vinyl ethers and crosslinking, preferably heterocyclic divinyl ethers.

主权项

1. A polymer based on a copolymer, which is in the form of polymeric particles, comprising
a) at least one hydrophilically substituted alkyl vinyl ether of formula IwhereR1, R2, R3, independently of one another, is H or C1 to C6 alkyl, andR4 is a radical which carries at least one hydroxyl group,
and b) at least one crosslinking agent of formula II and/or III and/or IVwhereX is a divalent alkyl radical having 2 to 5 C atoms in which one or more methylene groups which are not adjacent and are not located in the direct vicinity of N may be replaced by O, C═O, S, S═O, SO2, NH, NOH or N and one or more H atoms of the methylene groups may be substituted, independently of one another, by hydroxyl, C1-C6-alkyl, halogen, NH2, C5-C10-aryl, NH—(C1-C8)-alkyl, N—(C1-C8)-alkyl2, C1-C6-alkoxy or C1-C6-alkyl-OH,whereY1 and Y2 in formula III and IV
are, independently of one another, C1 to C10 alkyl or cycloalkyl, where one or more non-adjacent methylene groups or methylene groups which are not located in the direct vicinity of N may be replaced by O, C═O, S, S═O, SO2, NH, NOH or N and one or more H atoms of the methylene groups may be substituted, independently of one another, by hydroxyl, C1-C6-alkyl, halogen, NH2, C5-C10-aryl, NH(C1-C8)alkyl, N(C1-C8)alkyl2, C1-C6-alkoxy or C1-C6-alkyl-OH, or C6 to C18 aryl, where one or more H atoms in the aryl system may be substituted, independently of one another, by hydroxyl, C1-C6-alkyl, halogen, NH2, NH(C1-C8)alkyl, N(C1-C8)alkyl2, C1-C6-alkoxy or C1-C6-alkyl-OH, and A is a divalent alkyl radical having 2 to 5 C atoms in which one or more non-adjacent methylene groups or methylene groups which are not located in the direct vicinity of N may be replaced by O, C═O, S, S═O, SO2, NH, NOH or N and one or more H of the methylene groups may be substituted, independently of one another, by hydroxyl groups, C1-C6-alkyl, halogen, NH2, C5-C10-aryl, NH(C1-C8)alkyl, N(C1-C8)alkyl2, C1-C6-alkoxy or C1-C6-alkyl-OH,wherein a) and b) have been copolymerized and the resultant polymer is in the form of polymeric particles,wherein at least one of the following conditions I to IV is satisfiedI) the polymer is porous having pore sizes between 2 and 200 nm,II) the polymer is in the form of particles having a diameter between 3 and 300 μm,III) b) is a crosslinking agent of formula II, orIV) b) is a crosslinking agent of formula IV.