Enhancing fermentation of starch- and sugar-based feedstocks

摘要

Provided are methods, systems, and compositions for increasing the rate and/or yield of fermentation processes using blended feedstocks. Also provided are methods, systems, and compositions for decreasing the yield of one or more undesirable products during fermentation.

主权项

1. A method of producing one or more fermentation end-products comprising:
(a) combining a composition comprising a biomass and a liquid, with a solution comprising a cellulosic hydrolysate comprising about 10% to about 70% w/v of C6 monosaccharides to produce a blended feedstock; (b) contacting the blended feedstock with one or more biocatalysts; and (c) fermenting the blended feedstock to produce one or more fermentation end-products; wherein the biomass comprises corn, corn mash, sugar cane, sugar beets, sugar palms, sweet sorghum, nypa palm, cassava, rice, milo, sorghum, sweet potatoes, wheat, molasses, tubers, roots, stems, whole grains, barley, rye, milo, sago, cassava, tapioca, rice, peas, beans, potatoes, beets, fruits, or a combination thereof, and wherein the cellulosic hydrolysate is prepared by a method comprising
pretreating liqnocellulosic material with hot water or dilute acid to solubilize hemicellulose in the liqnocellulosic material,substantially separating the solubilized hemicellulose from remaining lignocellulosic solids, andenzymatically hydrolyzing cellulose in the remaining lignocellulosic solids to obtain the cellulosic hydrolysate, wherein less than 20% of the total saccharides in the cellulsoic hydrolysate are C5 saccharides.