| 发明名称 |
MicroRNA-140-5p as a tumor suppressor and sensitizing agent for chemotherapy |
| 摘要 |
The present invention provides a method of improving a therapeutic response to a cancer treatment, in a subject, the method comprising administering an effective amount of an agent that enhances the expression of microRNA-140-5p or an agent that mimics the effects of microRNA-140-5p. Further provided is a method of treating a cancer in a subject in need of such treatment comprising the step of administering an effective amount of a microRNA-140-5p or an agent that enhances the expression of microRNA-140-5p. |
| 申请公布号 |
US8765707(B2) |
申请公布日期 |
2014.07.01 |
| 申请号 |
US201213453553 |
申请日期 |
2012.04.23 |
| 申请人 |
University of Houston System;Baylor College of Medicine |
发明人 |
Gunaratne Preethi H.;Shohet Jason M. |
| 分类号 |
C12N15/11 |
主分类号 |
C12N15/11 |
| 代理机构 |
|
代理人 |
Adler Benjamin Aaron |
| 主权项 |
1. A method for improving a response to a therapy for neuroblastoma in a subject, comprising the step of:
administering an effective amount of microRNA-140-5p to the subject. |
| 地址 |
Houston TX US |
