发明名称 Multi-field charged particle cancer therapy method and apparatus
摘要 The invention comprises a multi-field charged particle irradiation method and apparatus. Radiation is delivered through an entry point into the tumor and Bragg peak energy is targeted to a distal or far side of the tumor from an ingress point. Delivering Bragg peak energy to the distal side of the tumor from the ingress point is repeated from multiple rotational directions. Preferably, beam intensity is proportional to radiation dose delivery efficiency. Preferably, the charged particle therapy is timed to patient respiration via control of charged particle beam injection, acceleration, extraction, and/or targeting methods and apparatus. Optionally, multi-axis control of the charged particle beam is used simultaneously with the multi-field irradiation. Combined, the system allows multi-field and multi-axis charged particle irradiation of tumors yielding precise and accurate irradiation dosages to a tumor with distribution of harmful irradiation energy about the tumor.
申请公布号 US8766217(B2) 申请公布日期 2014.07.01
申请号 US200912994130 申请日期 2009.05.21
申请人 发明人 Balakin Vladimir Yegorovich
分类号 A61N5/10 主分类号 A61N5/10
代理机构 Perkins Coie LLP 代理人 Glenn Michael A.;Perkins Coie LLP
主权项 1. A method for irradiating a tumor of a patient with charged particles, comprising the steps of: delivering the charged particles with a charged particle therapy system, comprising: a synchrotron;an extraction foil;a charged particle beam path; anda rotatable platform, wherein said charged particle beam path runs through said synchrotron and above said rotatable platform; controlling intensity of the charged particles using a current originating at said extraction foil, said extraction foil positioned in the charged particle beam path after entry into said synchrotron and prior to a Lambertson extraction magnet, wherein electrons of said current originate in atoms of said extraction foil; actively scanning the charged particles along at least three axes, wherein said at least three axes comprise: a horizontal axis, a vertical axis, and an applied energy axis; during an irradiation period, rotating said rotatable platform to at least five irradiation positions covering at least ninety degrees of rotation of said rotatable platform; timing delivery of the charged to the tumor using a respiration signal, wherein a respiration command is sent to the patient using a display monitor, said display monitor configured to co-rotate with said rotatable platform, said respiration signal monitor respiration of the patient; and irradiating the tumor with the charged particles during each of said at least five irradiation positions.
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