METHOD OF MANUFACTURING POLYMETHOXYFLAVONES

摘要

PROBLEM TO BE SOLVED: To provide a method of manufacturing polymethoxyflavones excellent in storage stability and solubility in high purity from extractions of plants of the genus Citrus obtained by supercritical fluid extraction.SOLUTION: A method of manufacturing soluble polymethoxyflavones includes following processes: (A) a process of obtaining an extract A from plants of the genus Citrus by an extraction operation with supercritical fluid and a cosolvent; (B) a process of obtaining an extract B which the cosolvent is removed from the extract A by a concentration operation; (C) a process of obtaining an extract C from the extract B by an extraction operation with an ethanol solution; (D) a process of obtaining polymethoxyflavones by purifying the extract C or a dilution which the ethanol solution is added to the extract C with a porous material.