METHOD OF PRODUCING SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUND, AND SYNTHETIC INTERMEDIATE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide a method of producing, in an industrially efficient manner, substituted dihalo pyrazolopyrimidine compounds suitable for production of pharmaceuticals or the like.SOLUTION: This invention provides a method of producing a compound represented by formula II, where a ring A is heteroaryl which may be substituted, or salt thereof, the method including causing a specific 3-amino diazole compound or salt thereof with malonate or Meldrum's acid or salt thereof in the presence of halogenation agent.