SYSTEMS AND METHODS FOR ADJUSTING ELECTRICAL NEUROMODULATION THERAPY IN MEDICATION THERAPEUTIC WINDOW

摘要

A neuromodulation system and method for managing electrical neuromodulation therapy for a patient in conjunction with administering a pharmacological agent to the patient. Electrical energy is delivered to a target tissue region of the patient, thereby electrically modulating the target tissue region providing therapy to the patient. The energy level of the electrical energy delivered to the tissue is automatically varied inversely to the effect of the pharmacological agent on the patient during a therapeutic window. An absorption level of the pharmacological agent in the patient may be continually detected, and the energy level of the delivered electrical energy automatically varied based on the detected absorption level of the pharmacological agent during a therapeutic window.

主权项

1. A neuromodulation system for managing electrical neuromodulation therapy for a patient in conjunction with administering a pharmacological agent to the patient, the neuromodulation system comprising:
output modulation circuitry configured for delivering electrical energy to a target tissue region of the patient, thereby electrically modulating the target tissue region providing therapy to the patient; and a controller/processor configured for automatically instructing the output modulation circuitry to vary the energy level of the electrical energy delivered to the tissue inversely to the effect of the pharmacological agent on the patient during a therapeutic window.